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Best cough colds - October 2025

Last Updated - October 27, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, Relieves Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

Vicks

$19.97

More Details
Main highlights
- WORLD'S TOP SELLING OTC COUGH AND COLD BRAND: Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS: Life doesn't stop when you have a cold; NyQuil and DayQuil SEVERE Honey tackle your most bothersome cold & flu symptoms
- POWERFUL, MAXIMUM STRENGTH 9-SYMPTOM RELIEF DAY AND NIGHT: Use non-drowsy DayQuil SEVERE Honey for daytime and at night try NyQuil SEVERE Honey for fast relief so you can rest
- POWERFUL COLD & FLU RELIEF: DayQuil and NyQuil SEVERE Honey formulas are flavored with real honey & temporarily relieve common cold & flu symptoms
- GREAT-TASTING HONEY FLAVORED DAYQUIL AND NYQUIL: Get the same cold & flu relief you expect from DayQuil & NyQuil SEVERE in a great-tasting honey-licious flavor
$19.97
2
15% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

MAJOR
15% Off

MAJOR Cough and Cold HBP Tablets - Antihistamine and Cough Suppressant for People with High Blood Pressure - Dextromethorphan HBr, Chlorpheniramine Maleate - 16 Count (6 Pack)

MAJOR

$15.10

$17.95
(15% Off)

More Details
Main highlights
- SPECIALLY FORMULATED FOR HBP: The active ingredients in these cough and cold tablets may help reduce symptoms of a cold in those with high blood pressure.
- QUALITY FORMULATION: We maintain high standards of care through strict regulatory compliance to deliver carefully formulated, effective cough and cold tablets. With a dextromethorphan and chlorpheniramine formula, our tablets may help reduce symptoms of the common cold.
- MAJOR PHARMACEUTICALS: At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering quality OTC and vitamin supplements.
- COUGH AND COLD: Introducing Major Cough and Cold Support, a trusted remedy that may help provide temporary relief from symptoms of the common cold including cough, runny nose, and sneezing.
- ACTIVE INGREDIENTS: These cold tablets contain 30g dextromethorphan HBr cough suppressant and 4g chlorpheniramine maleate antihistamine. They are free of gelatin, starch, gluten, and nuts.
$15.10
$17.95 (15% Off)
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

Amazon Basic Care

$10.48

More Details
Main highlights
- PAIN RELIEVER AND FEVER REDUCER: Both Daytime and Nighttime cold medicine contain acetaminophen to help relieve aches, fever and sore throat
- NON-DROWSY DAYTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, nasal congestion, cough, and minor aches and pains
- NIGHTTIME COLD AND FLU MEDICINE provides multi-symptom relief of headache, fever, sore throat, sneezing, runny nose, cough, and minor aches and pains
- COLD AND FLU: Influenza (flu) and the common cold are respiratory illnesses caused by viruses. A cold medicine like Cold & Flu Relief Multi-Symptom Daytime/Nighttime can help
- ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Cold & Flu and Vicks NyQuil Cold & Flu
$10.48
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Coricidin HBP

Coricidin HBP Decongestant-Free Cough and Cold Medicine - Specially Designed Relief for High Blood Pressure, Cough, Runny Nose, Sneezing and Cold Symptoms (16 Count)

Coricidin HBP

$8.99

More Details
Main highlights
- The no.1 brand that gives powerful cold symptom relief without raising your blood pressure
- Provides fast, powerful cold relief for people with high blood pressure
- HSA/FSA Eligible -- Check your plan for coverage.
- Decongestant free, cough cold medicine
- Cold medicine comes in tablet form
- Cold and cough medicine for adults that relieves cough, runny nose, and sneezing
$8.99
5
Best Value
28% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
28% Off

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

Tylenol

$7.67

$10.67
(28% Off)

More Details
Main highlights
- This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
- From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
- Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
- Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
- 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
$7.67
$10.67 (28% Off)

Best cough colds - October 2025

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, Relieves Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

MAJOR Cough and Cold HBP Tablets - Antihistamine and Cough Suppressant for People with High Blood Pressure - Dextromethorphan HBr, Chlorpheniramine Maleate - 16 Count (6 Pack)

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

Coricidin HBP Decongestant-Free Cough and Cold Medicine - Specially Designed Relief for High Blood Pressure, Cough, Runny Nose, Sneezing and Cold Symptoms (16 Count)

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

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