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Best topical antimicrobials - June 2026

Last Updated - June 3, 2026

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

SkinSmart Antimicrobial

SkinSmart Antimicrobial Wound Therapy, Hypochlorous Acid Safely Removes Bacteria so Wounds Can Heal, 8 Ounce Clear Spray

SkinSmart Antimicrobial

$17.99

More Details
Main highlights
- TARGET BACTERIA: SkinSmart targets the #1 problem in wounds—bacteria. Safely remove bacteria without irritating skin or wounds, or interfering with your skin’s natural healing process
- SkinSmart’s Hypochlorous Acid may smell a bit like bleach, but it is NOT the same. The chemical formulas are completely different. SkinSmart is approved for use on eyelids---bleach is NOT.
- PROMOTES HEALING. Great for burns, rashes, boils, tattoos, and piercings. Use after cosmetic procedures and for post-op recovery. Safe for daily use
- DELIVERS THE HEALING BENEFITS OF HYPOCHLOROUS in a simple spray. A safe alternative to chlorohexidine, alcohol, and harsh antiseptics
- ALL-NATURAL HYPOCHLOROUS IS USED IN WOUND CENTERS AND BURN UNITS, now available in SkinSmart for at-home care, No rX required! In rare cases, a mild stinging sensation may occur. Do not use in case of known hypersenstivity to any constituent. Do not freeze. Actual Product Style and Design may vary.
$17.99
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

CareAll

CareAll Triple Antibiotic Ointment (144 Pack), 0.9gr Foil Packet. First Aid Ointment That Prevents Infection in Minor Cuts, Scrapes, and Burns

CareAll

$11.67

More Details
Main highlights
- SINGLE USE each 0.9 gram foil packet is easy to dispense.
- FORMULATED with you in mind. CareALL Triple Antibiotic ingredients are phthalate-free, paraben-free, dye-free, and fragrance-free.
- FIRST AID ANTIBIOTIC OINTMENT for the prevention of infections in minor cuts, scrapes and burns.
- FDA REGISTERED with NDC# (National Drug Code Number) printed on packaging with LOT # and Expiration Date. For External Use Only.
- ACTIVE INGREDIENTS Compare to the Active Ingredients of Leading Brand. Active Ingredients (in each gram): Bacitracin Zinc 400 units, Neomycin Sulfate 5mg (equivalent to 3.5mg of Neomycin base), Polymyxin B Sulfate 5,000 units.
$11.67
3
Best Value
20% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Neosporin
20% Off

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

Neosporin

$9.88

$12.39
(20% Off)

More Details
Main highlights
- Sting-free formula: Fragrance-free, Neosporin + Pain Relief Dual Action Antibiotic Cream applies to skin easily, absorbs quickly without residue, and won't stain fabrics, supporting comfortable daily wound care for minor cuts, scrapes, and burns
- Pain relief analgesic: Pramoxine HCl provides maximum-strength pain relief as an external analgesic in a non-greasy, stain-free, no-sting formula that soothes discomfort from minor scrapes, burns, and cuts
- First-aid cream convenience: Includes one 1 oz tube (sold individually) for easy portability in backpacks, purses, and travel kits; apply one to three times daily after cleansing the affected area for straightforward, on-the-go wound care
- Complete wound care: Dual-action antibiotic cream and external analgesic help prevent infection for 24-hour protection and soothe pain in minor wounds; pair with a BAND-AID Brand sterile bandage after application for best results in first-aid kits
- Antibiotic cream: Neomycin sulfate and polymyxin B sulfate deliver dual antibiotic action with up to 24-hour protection in a first-aid cream, helping prevent infection from minor cuts, scrapes, and burns when used as directed
$9.88
$12.39 (20% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Globe

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to the Active Ingredients of the Leading Brand.

Globe

$7.32

More Details
Main highlights
- WHATS INSIDE: Globe Triple Antibiotic Ointment contains the same active antibiotic ingredients as the leading name brand: neomycin, bacitracin and polymyxin. It provides 24-hour protection against infection in minor cuts scrapes and burns.
- VALUE PACK: Globe Triple Antibiotic Ointment Value Pack comes with 4 single 1 oz tubes. The Globe Triple Antibiotic Value pack includes 4 individual tubes (1 oz each- a total of 4 oz) to take with you anywhere.
- QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. US FDA audited manufacturing facilities. Trifecta Pharmaceuticals USA is a family business based in sunny Fort Lauderdale, Florida USA.
- INFECTION PROTECTION: Globe Triple Antibiotic Ointment helps to soothe painful cuts, scrapes, and burns while preventing infection. 100% Infection Protection!! Healing Ointment
- FIRST AID KIT: Globe Triple Action Antibiotic ointment is a must have product in your first aid kit. Its a skin care treatment for minor cuts, scrapes, and burns. Frist class First Aid Treatment for Minor Cuts, Scars, Eczema, Scraps, and Burns. Perfect Healing Ointment for your First Aid Cabinet.
- EASY TO TAKE WITH YOU: Keep Globes Triple Antibiotic Ointment 4 tubes Value Pack in your medicine closet, car, camping bag, purse, kitchen drawer, kid's backpack, and even your travel carryon luggage. The convenience of the tube size can go with you anywhere.
$7.32
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Neosporin

Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical Pain Relief, 24-Hour Infection Protection That Numbs Away The Pain for Minor Wound Care, 1 oz

Neosporin

$9.99

$10.98
(9% Off)

More Details
Main highlights
- Triple antibiotic ointment also contains fast-acting lidocaine, a topical analgesic that numbs away the pain, for maximum-strength burn pain relief and long-lasting infection protection from painful minor cuts, scrapes, burns, and wounds
- To use, clean affected area with a BAND-AID Brand Antiseptic Spray and treat with a small amount of first aid topical antibiotic ointment one to three times daily. Cover the minor wound with a BAND-AID Brand Adhesive Bandage for extra protection
- Pain relief ointment formulated with triple antibiotic combination of infection-protection ingredients bacitracin zinc, neomycin sulfate and polymyxin B sulfate to help prevent infections in minor cuts, scrapes, and wounds for minor wound care treatment
- First aid essential in a compact and portable 1-ounce tube, suitable in wound care supplies and first aid kits for home, on-the-go, cars, dorms, travel, camping, and outdoors, provides effective triple antibiotic protection for treatment of minor wounds
- 1-ounce tube of Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, by the #1 doctor-recommended brand, has an effective germ-killing formula for 24-hour long-lasting infection protection and fast-acting numbing pain relief for minor wounds
$9.99
$10.98 (9% Off)

Best topical antimicrobials - June 2026

SkinSmart Antimicrobial Wound Therapy, Hypochlorous Acid Safely Removes Bacteria so Wounds Can Heal, 8 Ounce Clear Spray

CareAll Triple Antibiotic Ointment (144 Pack), 0.9gr Foil Packet. First Aid Ointment That Prevents Infection in Minor Cuts, Scrapes, and Burns

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic and Analgesic Cream for Soothing Infection Protection & Wound Care of Minor Cuts, Scrapes & Burns, 1 oz

Globe Triple Antibiotic Ointment 1.0 oz (4 Pack), First Aid Ointment for Minor Scrapes, Cuts, and Burns to Help Prevent Infection, Compare to the Active Ingredients of the Leading Brand.

Neosporin + Lidocaine First Aid Triple Antibiotic Ointment, Fast-Acting, Maximum Strength Topical Pain Relief, 24-Hour Infection Protection That Numbs Away The Pain for Minor Wound Care, 1 oz

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Neosporin Original First Aid Antibiotic Ointment for Wounds, Infection Protection Treatment, Germ-Killing Formula, Helps Minimize Appearance Of Scars for Minor Cuts, Scrapes, Burns, 1 Oz

Band-Aid Brand Pain Relieving Antiseptic Cleansing Spray, Pramoxine HCl, 8 fl. Oz

Neosporin + Maximum-Strength Pain Relief Ointment, Triple Antibiotic, Soothing Infection Protection, No-Sting Topical First Aid Wound Care for Minor Cuts, Scrapes & Burns, 1 Oz Tube

CareAll Triple Antibiotic Ointment 1.0 oz (3 Pack), First Aid Ointment for Minor Cuts, Scrapes, and Burns to Help Prevent Infection, Compare to The Active Ingredients of Leading Brands

Hibiclens – Antimicrobial and Antiseptic Soap and Skin Cleanser – 8 oz with Foaming Pump – for Home and Hospital – 4% CHG

Neosporin Original First Aid Triple Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Helps Minimize The Appearance of Scars for Minor Wounds, .5 oz

CareAll Triple Antibiotic Ointment (25 Pack), 0.9gr Foil Packet. First Aid Ointment That Prevents Infection in Minor Scrapes, Cuts, and Burns

Bacitracin Antibiotic Ointment with Zinc USP - 1 oz Topical Antibiotic First Aid Ointment - Helps Prevent Infection in Minor Cuts, Scrapes, and Burns

Thera|Care Triple Antibiotic Ointment | First Aid | Infection Prevention and Protection | 1.0 oz | Topical Wound Care for Minor Scrapes and Cuts

Polysporin First Aid Topical Antibiotic Skin Ointment with Bacitracin Zinc & Polymyxin B Sulfate, for Infection Protection & Wound Care, Neomycin-Free, Travel Size, 0.5 oz

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